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Structural domains of the insulin receptor and IGF receptor required for dimerisation and ligand binding

โœ Scribed by L Molina; C Marino-Buslje; D.R Quinn; K Siddle


Book ID
117101483
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
122 KB
Volume
467
Category
Article
ISSN
0014-5793

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โœ J. Murray-Rust; A. N. McLeod; T. L. Blundell; S. P. Wood ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 833 KB

Insulin is a member of a family of hormones, growth factors and neuropeptides which are found in both vertebrates and invertebrates. A common 'insulin fold' is probably adopted by all family members. Although the specificities of receptor binding are different, there is a possibility of co-evolution