Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering"
✦ LIBER ✦
Structural characterization of the maytansinoid–monoclonal antibody immunoconjugate, huN901–DM1, by mass spectrometry
✍ Scribed by Lintao Wang; Godfrey Amphlett; Walter A. Blättler; John M. Lambert; Wei Zhang
- Book ID
- 111752508
- Publisher
- Cold Spring Harbor Laboratory Press
- Year
- 2005
- Tongue
- English
- Weight
- 589 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0961-8368
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## Abstract Prostate‐specific antigen (PSA), a 237‐amino acid glycoprotein, encoded by the __hKLK3__ gene, is widely used as a serum marker for the diagnosis and management of prostate cancer. We report here the localization of a conformational epitope recognized by the anti‐total PSA monoclonal an