Antibody Engineering || Structural Characterization of Antibodies by Mass Spectrometry

✍ Scribed by Kontermann, Roland; Dübel, Stefan

• Book ID: 118055690
• Publisher: Springer Berlin Heidelberg
• Year: 2010
• Tongue: English
• Weight: 531 KB
• Edition: 2
• Category: Article
• ISBN: 3642011446
• DOI: 10.1007/978-3-642-01144-3_39

✦ Synopsis

Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.