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Structural Characterization of the Intramolecular Interaction between the SH3 and Guanylate Kinase Domains of PSD-95

✍ Scribed by Gisele A. Tavares; Ezequiel H. Panepucci; Axel T. Brunger


Book ID
117736686
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
773 KB
Volume
8
Category
Article
ISSN
1097-2765

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## Abstract **Background:** hDLG, the human homologue of the __Drosophila__ tumour suppressor __dlg__, functions as a scaffolding protein that facilitates the transmission of diverse downstream signals. hDLG possesses multiple protein‐binding domains, including three PDZ domains, an SH3 domain, a H