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Structural biology in fragment-based drug design

✍ Scribed by Christopher W Murray; Tom L Blundell


Book ID
113883345
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
989 KB
Volume
20
Category
Article
ISSN
0959-440X

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## Abstract In cooperation with the fragment‐based design a new drug design method, the so‐called “fragment‐based quantitative structure–activity relationship” (FB‐QSAR) is proposed. The essence of the new method is that the molecular framework in a family of drug candidates are divided into severa