Fragment-based quantitative structure–ac
Fragment-based quantitative structure–activity relationship (FB-QSAR) for fragment-based drug design
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Qi-Shi Du; Ri-Bo Huang; Yu-Tuo Wei; Zong-Wen Pang; Li-Qin Du; Kuo-Chen Chou
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 278 KB
## Abstract In cooperation with the fragment‐based design a new drug design method, the so‐called “fragment‐based quantitative structure–activity relationship” (FB‐QSAR) is proposed. The essence of the new method is that the molecular framework in a family of drug candidates are divided into severa