## Abstract Signal transducer and activator of transcription 3 (Stat3) is constitutively active in a number of cancers where it participates in aberrant transcription of prosurvival, cell cycling, and angiogenesis genes. Since Stat3 initiates its signaling activity through binding of its SH2 domain
β¦ LIBER β¦
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
β Scribed by Fesik, Stephen W.; Liu, Zhihong; Sun, Chaohong; Olejniczak, Edward T.; Meadows, Robert P.; Betz, Stephen F.; Oost, Thorsten; Herrmann, Julia; Wu, Joe C.
- Book ID
- 109773004
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 375 KB
- Volume
- 408
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/35050006
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