A model for the catalytic site of F1-ATPase based on analogies to nucleotide-binding domains of known structure

A model for the nucleotide-binding domai

A model for the nucleotide-binding domains of ABC transporters based on the large domain of aspartate aminotransferase

✍ Flip J. Hoedemaeker; Alan R. Davidson; David R. Rose 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 638 KB

ABC transporters are a large superfamily of integral membrane proteins involved inATP-dependent transport across biological membranes. Members of this superfamily play roles in a number of phenomena of biomedical interest, including cystic fibrosis (CFTR) and multidrug resistance (P-glycoprotein, MR