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Structural and functional characterization of the upstream regulatory region of the human gene encoding prostate apoptosis response factor-4

✍ Scribed by Shu-Chi Hsu; Ford Kirschenbaum; Judy Miller; Barbara Cordell; Justin V. McCarthy


Book ID
117521009
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
239 KB
Volume
295
Category
Article
ISSN
0378-1119

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## Abstract We isolated the __p53__ gene from Syrian hamster embryo cells by cosmid cloning procedures. The organization of the hamster __p53__ gene was similar to that of other mammalian __p53__ genes; it had 11 exons, a noncoding exon 1, and a long intron 1 (about 6.5 kb). The upstream __p53__ pr