Structural and functional aspects of RGD-containing protein antagonists of glycoprotein IIb-IIIa
β Scribed by Robert A. Lazarus; Robert S. McDowell
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 880 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Arg-Gly-Asp (RGD)-containing peptides and the peptide unique to fibrinogen in the C-terminal domain of the gamma chain are important for fibrinogen binding to platelet membrane glycoprotein (GP) II b/III a. We synthesized a unique hybrid peptide of YRGDSPLGGAKQAGDV encompassing the RGD sequence (RGD
## Abstract We report on two cases of acute coronary stent thrombosis after early withdrawal of different competitive inhibitors of the platelet glycoprotein IIb/IIIa receptor, eptifibatide and tirofiban. Differences in pharmacokinetics between different types of glycoprotein IIb/IIIa receptor bloc