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Structural and functional analyses of DNA bending induced by Sp1 family transcription factors

✍ Scribed by Eva Sjøttem; Cecilie Andersen; Terje Johansen

Book ID
115627823
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
746 KB
Volume
267
Category
Article
ISSN
0022-2836

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Bending of DNA by transcription factors
Bending of DNA by transcription factors
✍ Peter C. van der Vliet; C. Peter Verrijzer 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 805 KB

An increasing number of transcription factors both from prokaryotic and eukaryotic sources are found to bend the DNA upon binding to their recognition site. Bending can easily be detected by the anomalous electrophoretic behaviour of the DNA-protein complex or by increased cyclization of DNA fragmen