Synthesis of 8-[18O]hydroxy-2β²-deoxyguan
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R. C. A. Hermanns; G. Zomer; M. Jacquemijns; J. F. C. Stavenuiter; J. G. Westra;
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Article
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1994
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John Wiley and Sons
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French
β 390 KB
π 1 views
## Abstract 8β[^18^O]Hydroxyβ2β²βdeoxyguanosine was synthesized starting from 8βbromoβ2β²βdeoxyguanosine and the sodium salt of [^18^O]benzyl alcohol, resulting in the intermediate 8β[^18^O]benzyloxyβ2β²βdeoxyguanosine. Subsequent reduction by catalytic transfer hydrogenation, yielded the desired prod