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Solution Structure of a DNA Duplex Containing 8-Hydroxy-2′-Deoxyguanosine Opposite Deoxyguanosine

✍ Scribed by Varatharasa Thiviyanathan; Anoma Somasunderam; Tapas K. Hazra; Sankar Mitra; David G. Gorenstein


Book ID
117143145
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
632 KB
Volume
325
Category
Article
ISSN
0022-2836

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Synthesis of 8-[18O]hydroxy-2′-deoxyguan
✍ R. C. A. Hermanns; G. Zomer; M. Jacquemijns; J. F. C. Stavenuiter; J. G. Westra; 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 390 KB 👁 1 views

## Abstract 8‐[^18^O]Hydroxy‐2′‐deoxyguanosine was synthesized starting from 8‐bromo‐2′‐deoxyguanosine and the sodium salt of [^18^O]benzyl alcohol, resulting in the intermediate 8‐[^18^O]benzyloxy‐2′‐deoxyguanosine. Subsequent reduction by catalytic transfer hydrogenation, yielded the desired prod