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Structural Analysis of the Substoichiometric and Stoichiometric Microtubule-Inhibiting Biphenyl Analogues of Colchicine †

✍ Scribed by Rossi, Miriam; Gorbunoff, Marina J.; Caruso, Francesco; Wing, Bernadette; Perez-Ramirez, Bernardo; Timasheff, Serge N.

Book ID
127309886
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
221 KB
Volume
35
Category
Article
ISSN
0006-2960

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Stereochemical Variations on the Colchicine Motif. Part 3.The First Colchicine Analogues with an Eight-Membered B-Ring. Structure, Optical Resolution and Inhibition of Microtubule Assembly. -The desired title compound is prepared and investigated by X-ray crystal analysis. The enantiomeric resolutio