Patients with chronic renal failure undergoing hemodialysis who are infected with hepatitis C virus (HCV) may test consistently anti-HCV negative. Because CD4(+) T-cells provide help for antibody production virus-specific effector CD4(+) T-cell responses were investigated in relation to anti-HCV pos
Stronger hepatitis C virus-specific CD8+ T-cell responses in HIV coinfection
β Scribed by L. Barrett; M. Gallant; C. Howley; M. Ian Bowmer; G. Hirsch; K. Peltekian; M. Grant
- Book ID
- 108886440
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 306 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1352-0504
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Hepatitis C virus (HCV) causes chronic infection accompanied by a high risk of liver failure and hepatocellular carcinoma. CD8Ψ T cell responses are important in the control of viremia. However, the T cell response in chronic infection is weak both in absolute numbers and in the range of epitopes ta
By necessity, human liver transplantation is performed across HLA barriers. As a result, intracellular infection of the allograft presents a unique immunologic challenge for the recipient's immune system. In this study, we describe the presence of HLA-A2-restricted, hepatitis C virus (HCV)-specific