𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection

✍ Scribed by Hans Christian Spangenberg; Sergei Viazov; Nadine Kersting; Christoph Neumann-Haefelin; Denise McKinney; Michael Roggendorf; Fritz von Weizsäcker; Hubert E. Blum; Robert Thimme


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
276 KB
Volume
42
Category
Article
ISSN
0270-9139

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Upregulation of endogenous intrahepatic
✍ Gerry C. MacQuillan; Cyril Mamotte; William D. Reed; Gary P. Jeffrey; Jane E. Al 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB

## Abstract The success of interferon‐α and ribavirin combination therapy for the treatment of chronic hepatitis C viral infection differs between patients. In an attempt to identify predictors of host response to therapy, the levels of mRNA for interferon (IFN) stimulated genes: MxA, PKR, 2′5′ OAS

T-cell–mediated autologous hepatocytotox
✍ Yun-Fan Liaw; Ching-Song Lee; Sun-Lung Tsai; Bo-Wen Liaw; Tse-Ching Chen; I-Shya 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 700 KB

Virus-specific cytotoxic T lymphocytes (CTLs) have been suggested to be responsible for the liver injuries in patients with hepatitis C virus (HCV) infection. However, there has been no report of direct evidence to substantiate this hypothesis. In this study, we performed in vitro autologous hepatoc

CD8+ T lymphocyte responses are induced
✍ Franziska Lechner; Norbert H. Gruener; Simona Urbani; Jacopo Uggeri; Teresa Sant 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 176 KB 👁 1 views

Cellular immune responses are likely to play a key role in determining the clinical outcome in acute infection with hepatitis C virus (HCV), but the dynamics of such responses and their relationship to viral clearance are poorly understood. In a previous study we have shown highly activated, multisp

Intrahepatic MxA and PKR protein express
✍ Gerry C. MacQuillan; W. Bastiaan de Boer; Michael A. Platten; Kieran A. McCaul; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 419 KB

The therapeutic effect of interferon-alpha and ribavirin in the treatment of chronic hepatitis C viral infection is limited. To identify patient characteristics that may predict responsiveness to treatment, the intrahepatic protein expression of two directly induced IFN-alpha effector proteins, MxA