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Strong associations of short-chain perfluoroalkyl acids with serum albumin and investigation of binding mechanisms

โœ Scribed by Heather N. Bischel; Laura A. MacManus-Spencer; Chaojie Zhang; Richard G. Luthy


Book ID
102198348
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
131 KB
Volume
30
Category
Article
ISSN
0730-7268

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Chiral discrimination of racemic carbazole carbonyl (CC)-amino acids with linear alkyl sidechain (C 1 -C 4 ) by bovine serum albumin (BSA) was investigated by competitive replacement experiments using dansyl-L-proline and dansyl-D-norvaline as fluorescent probes. It was found that the CC derivatives