Stromal cell growth and blast colony-forming cells in AML bone marrow
✍ Scribed by Y. El-Khatib; Julia Gidáli; I. Fehér; Anna Mód; Anna Poros; Susan Hollán
- Book ID
- 113239349
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 398 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0145-2126
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## Abstract Colony‐forming efficiency (CFE) was used to monitor the proliferative response of alkaline phosphatase‐positive rabbit bone marrow stromal cells to acute blood loss. The CFE of animals subjected to a 1% blood loss was 0.97 compared with 0.06 (p < 0.01) in nonbled animals. Sera obtained
Human bone marrow contains a population of haemopoietic progenitor cells that can be distinguished by their ability to adhere to preformed stromal layers (cultured in the presence of methylprednisolone [MP+] and form blast cell colonies. The stromal layers function in the colony assay after they hav