Stromal cell-derived factor-1 binding to its chemokine receptor CXCR4 on precursor cells promotes the chemotactic recruitment, development and survival of human osteoclasts

Contribution of genetic polymorphisms of

Contribution of genetic polymorphisms of stromal cell–derived factor-1 and its receptor, CXCR4, to the susceptibility and clinicopathologic development of oral cancer

✍ Ying-Hock Teng; Te-Hsiung Liu; Hsien-Chun Tseng; Tsung-Te Chung; Chia-Ming Yeh; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 136 KB 👁 1 views

## Abstract ## __Background.__ The aim of this study was to evaluate the relations of __SDF‐1__ and its receptor, CXCR4, gene variants on oral cancer risk. ## __Methods.__ PCR‐RFLP was used to measure __SDF‐1__‐3′A and __CXCR4__ gene polymorphisms in 284 controls and 113 patients with oral cance