✦ LIBER ✦

Striterfit, a least-squares pharmacokinetic curve-fitting package using a programmable calculator

✍ Scribed by Donald P. Thornhill; Eric Schwerzel

Publisher: John Wiley and Sons
Year: 1985
Tongue: English
Weight: 401 KB
Volume: 74
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600740510

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✦ Synopsis

A program is described that permits iterative least-squares nonlinear regression fitting of polyexponential curves using the Hewlett Packard HP 41 CV programmable calculator. The program enables the analysis of pharmacokinetic drug level profiles with a high degree of precision. Up to 15 data pairs can be used, and initial estimates of curve parameters are obtained with a stripping procedure. Up to four exponential terms can be accommodated by the program, and there is the option

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