Regulation of DNA repair gene expression
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Claire J. McGurk; Michele Cummings; Beate Köberle; John A. Hartley; R. Timothy O
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Article
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2006
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John Wiley and Sons
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English
⚖ 349 KB
👁 1 views
## Abstract Although most advanced cancers are incurable, the majority of testicular germ cell tumors can be cured using cisplatin‐based combination chemotherapy. The nucleotide excision repair (NER) pathway removes most DNA adducts produced by cisplatin, and the low levels of NER in testis tumor c