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Stringent Regulation of DNA Repair During Human Hematopoietic Differentiation: A Gene Expression and Functional Analysis

✍ Scribed by Tomke U. Bracker; Bernd Giebel; Jan Spanholtz; Ursula R. Sorg; Ludger Klein-Hitpass; Thomas Moritz; Jürgen Thomale


Book ID
111843609
Publisher
AlphaMed Press
Year
2006
Tongue
English
Weight
478 KB
Volume
24
Category
Article
ISSN
1066-5099

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## Abstract Although most advanced cancers are incurable, the majority of testicular germ cell tumors can be cured using cisplatin‐based combination chemotherapy. The nucleotide excision repair (NER) pathway removes most DNA adducts produced by cisplatin, and the low levels of NER in testis tumor c