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Striatal metabotropic glutamate receptors as a target for pharmacotherapy in Parkinson’s disease

✍ Scribed by P. Bonsi; D. Cuomo; B. Picconi; G. Sciamanna; A. Tscherter; M. Tolu; G. Bernardi; P. Calabresi; A. Pisani


Publisher
Springer
Year
2006
Tongue
English
Weight
224 KB
Volume
32
Category
Article
ISSN
0939-4451

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The subthalamic nucleus: A possible targ
✍ J. Guridi; M. R. Luquin; M. T. Herrero; Dr. J. A. Obeso 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 902 KB

## Abstract Hyperactivity in the subthalamic nucleus (STN) projections to the globus pallidus medialis (GPM) has been established as a crucial feature of parkinsonism in animal models of Parkinson's disease (PD). Recent experiments blocking the STN glutamatergic output to GPM or lesioning the STN s