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Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole hemisphere autoradiography

✍ Scribed by Erkki Tupala; Merja Häkkinen; Markus Storvik; Jari Tiihonen


Book ID
113866216
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
512 KB
Volume
163
Category
Article
ISSN
0925-4927

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## Abstract Increasing evidence implies the involvement of the dopamine (DA) system in the pathogenesis of alcoholism. We measured striatal DA D~2~ receptors in Cloninger type 1 and 2 alcoholics by using [^125^I]epidepride in human postmortem whole hemispheric autoradiography (WHA), which provides