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Measurement of the Striatal Dopamine Transporter Density and Heterogeneity in Type 1 Alcoholics Using Human Whole Hemisphere Autoradiography

✍ Scribed by Erkki Tupala; Jyrki T. Kuikka; Håkan Hall; Kim Bergström; Terttu Särkioja; Pirkko Räsänen; Tuija Mantere; Jukka Hiltunen; Jouko Vepsäläinen; Jari Tiihonen


Book ID
118769533
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
160 KB
Volume
14
Category
Article
ISSN
1053-8119

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## Abstract Increasing evidence implies the involvement of the dopamine (DA) system in the pathogenesis of alcoholism. We measured striatal DA D~2~ receptors in Cloninger type 1 and 2 alcoholics by using [^125^I]epidepride in human postmortem whole hemispheric autoradiography (WHA), which provides