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Striatal dopaminergic denervation and gait in healthy adults

✍ Scribed by R. Cham; S. A. Studenski; S. Perera; N. I. Bohnen


Book ID
105907745
Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
332 KB
Volume
185
Category
Article
ISSN
0014-4819

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Denervation-induced supersensitivity of the striatal dopamine receptors can be quantified by the turning behaviour induced by apomorphine. With this experimental model we found that high-dose L-dopa/carbidopa administration reduced this supersensitivity. This effect was seen on the 1st day and did n