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Striatal D2-dopamine receptor occupancy during treatment with typical and atypical neuroleptics

✍ Scribed by Joseph Scherer; Klaus Tatsch; Johannes Schwarz; Wolfgang Oertel; M.C. Kirsch; Margot Albus


Book ID
118856721
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
385 KB
Volume
36
Category
Article
ISSN
0006-3223

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Chronic neuroleptic treatment: D2 dopami
✍ Dr Paolo Calabresi; Marco De Murtas; Nicola Biagio Mercuri; Giorgio Bernardi 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 807 KB

## Abstract We studied the in vitro electrical activity of rat neostriatal neurons following chronic neuroleptic treatment. In haloperidol‐treated rats, unlike naive animals, activation of neostriatal D2 dopamine receptors induced a potent presynaptic inhibition of glutamate‐mediated excitatory syn