In an effort to identify novel binding sites for cocaine and its analogs, we carried out binding studies with the high-affinity and selective ligand [ 125 I]RTI-121 in rat frontal cortical tissue. Very low densities of binding sites were found. Saturation analysis revealed that the binding was to bo
โฆ LIBER โฆ
Striatal [125I]RTI-55 binding sites in cocaine-abusing humans
โ Scribed by Karley Y. Little; F.Ivy Carroll; John D. Butts
- Book ID
- 117449422
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 840 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0278-5846
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125 I]RTI-55 is a cocaine analog with high affinity for dopamine (DA) and serotonin (5-HT) transporters. Quantitative ligand binding studies revealed a novel high affinity [ 125 I]RTI-55 binding site assayed under 5-HT transporter (SERT) conditions which has low affinity for almost all classic biog
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