✦ LIBER ✦

Stress proteins and immunity mediated by cytotoxic T lymphocytes

✍ Scribed by Hansjörg Schild; Danièle Arnold-Schild; Eckhard Lammert; Hans-Georg Rammensee

Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 80 KB
Volume: 11
Category: Article
ISSN: 0952-7915
DOI: 10.1016/s0952-7915(99)80019-3

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✦ Synopsis

Chaperone molecules, including members of the heat shock protein family, are able to stimulate αβ and γδ T cells as well as natural killer cells. For αβ T cells, specificity is induced by chaperone-assisted peptides; this has lead to detailed investigations of peptides that bind to these chaperones and their possible role in antigen presentation.

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