Binding capacity of the cytoplasmic and nuclear glucocorticoid receptor (GR) and the activity of tyrosine aminotransferase (TAT) were examined in the liver of intact and adrenalectomized rats exposed to 41 C whole body hyperthermic stress. In glucocorticoid-deprived animals, stress-induced decrease
✦ LIBER ✦
Stress-induced changes of glucocorticoid receptor in rat liver
✍ Scribed by Alexandrová, M.; Farkaš, P.
- Book ID
- 122499096
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 507 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0960-0760
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## ABSTRACT A mild whole body hyperthermic stress causes a rapid and reversible reduction of rat liver glucocorticoid receptor (GR) binding capacity and affects the stability of the GR‐DNA complexes formed after thermal transformation of the receptor. These changes appear to be physiologically rele
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