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Streptokinase increases the sensitivity of colon cancer cells to chemotherapy by gemcitabine and cis-platine in vitro

✍ Scribed by Vladimir Bobek; Daniela Pinterova; Katarina Kolostova; Michael Boubelik; Joshua Douglas; Petr Teyssler; Jiri Pavlasek; Josef Kovarik


Book ID
116333813
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
298 KB
Volume
237
Category
Article
ISSN
0304-3835

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✍ Erica Miraglia; Daniele Viarisio; Chiara Riganti; Costanzo Costamagna; Dario Ghi πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 French βš– 141 KB πŸ‘ 1 views

## Abstract Multidrug resistant (MDR) tumor cells exhibit an altered pH gradient across different cell compartments, which favors a reduced intracellular accumulation of antineoplastic drugs and a decreased therapeutic effect. In our study, we have observed that the activity and expression of Na^+^