Streptococcal Cell Wall Arthritis: Kinetics of Immune Cell Activation in Inflammatory Arthritis
β Scribed by Donald Kimpel; Tim Dayton; Krishnaswamy Kannan; Robert E. Wolf
- Book ID
- 118768573
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 203 KB
- Volume
- 105
- Category
- Article
- ISSN
- 1090-2341
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## Joint inflammation initially induced by intraarticular injection of an aqueous suspension of pep tidoglycan-polysaccharide (PG-PS) fragments isolated from Streptococcus pyogenes was reactivated by systemic injection of a normally subarthropathic dose of homologous or heterologous cell wall poly
Endothelial cells play a fundamental role in the pathogenesis of chronic inflammatory arthritis in humans such as rheumatoid arthritis (RA), as well as experimental animal models such as streptococcal cell wall (SCW) arthritis in Lewis (LEW/N) rats. This review summarizes data in support of this con
Streptococcal cell wall (SCW)-induced arthritis is a chronic, erosive polyarthritis which can be induced in susceptible Lewis rats by one intraperitoneal injection of a sterile, aqueous suspension of SCW. The chronic phase of the disease is dependent on Tcells. Mercuric chloride is an immunomodulati