Splenectomy attenuates streptococcal cell wall–induced arthritis and alters leukocyte activation
✍ Scribed by Donald Kimpel; Tim Dayton; John Fuseler; Laura Gray; Krishnaswamy Kannan; Robert E. Wolf; Matthew Grisham
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 248 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Joint inflammation initially induced by intraarticular injection of an aqueous suspension of pep tidoglycan-polysaccharide (PG-PS) fragments isolated from Streptococcus pyogenes was reactivated by systemic injection of a normally subarthropathic dose of homologous or heterologous cell wall poly
## Abstract ## Objective To determine whether parathyroid hormone–related protein (PTHrP), an interleukin‐1β–inducible, bone‐resorbing peptide that is produced in increasing amounts by the synovium in rheumatoid arthritis (RA), may play a role in the pathophysiology of joint destruction in RA. ##
Streptococcal cell wall (SCW)-induced arthritis is a chronic, erosive polyarthritis which can be induced in susceptible Lewis rats by one intraperitoneal injection of a sterile, aqueous suspension of SCW. The chronic phase of the disease is dependent on Tcells. Mercuric chloride is an immunomodulati