𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Strategic use of preparative chiral chromatography for the synthesis of a preclinical pharmaceutical candidate

✍ Scribed by William R. Leonard Jr.; Derek W. Henderson; Ross A. Miller; Glenn A. Spencer; Osama S. Sudah; Mirlinda Biba; Christopher J. Welch


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
355 KB
Volume
19
Category
Article
ISSN
0899-0042

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The use of turbulent flow chromatography
✍ J. Ayrton; G. J. Dear; W. J. Leavens; D. N. Mallett; R. S. Plumb πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 114 KB πŸ‘ 2 views

The use of turbulent flow chromatography coupled to mass spectrometry (turbulent flow LC/MS) shows great potential for the rapid, direct analysis of pharmaceutical compounds in plasma and serum. The use of turbulent flow LC/MS has removed the need for any time-consuming sample preparation such as so

The application of preparative batch HPL
✍ Tony Q. Yan; Carlos Orihuela; David Swanson πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 328 KB

## Abstract This article discusses the chromatographic resolution of a racemic pharmaceutical intermediate. Preparative batch high performance liquid chromatography (HPLC), supercritical fluid chromatography (SFC), steady‐state recycling (SSR), and simulated moving bed (SMB) were used to resolve a