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Straightforward Stereoselective Synthesis of Spiro-epoxyoxindoles

✍ Scribed by Schulz, Verena; Davoust, Marion; Lemarié, Margareth; Lohier, Jean-François; Sopkova de Oliveira Santos, Jana; Metzner, Patrick; Brière, Jean-François


Book ID
118041699
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
93 KB
Volume
9
Category
Article
ISSN
1523-7060

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✍ Patricia Castejón; Albert Moyano; Miquel A. Pericàs; Antoni Riera 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 795 KB

A novel strategy for the synthesis of isostatine derivatives has been developed. Contrary to previous approaches to isostatine, a non-proteinogenic amino acid that is an essential component of the didemnins, the present synthesis does not require the intermediacy of the expensive amino acid D-do-iso