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Straightforward Stereoselective Synthesis of Spiro-epoxyoxindoles.

✍ Scribed by Verena Schulz; Marion Davoust; Margareth Lemarie; Jean-Francois Lohier; Jana Sopkova de Oliveira Santos; Patrick Metzner; Jean-Francois Briere

Publisher
John Wiley and Sons
Year
2007
Weight
36 KB
Volume
38
Category
Article
ISSN
0931-7597

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A Straightforward, Highly Stereoselectiv
A Straightforward, Highly Stereoselective Synthesis of Protected Isostatine Derivatives
✍ Patricia CastejΓ³n; Albert Moyano; Miquel A. PericΓ s; Antoni Riera πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 795 KB

A novel strategy for the synthesis of isostatine derivatives has been developed. Contrary to previous approaches to isostatine, a non-proteinogenic amino acid that is an essential component of the didemnins, the present synthesis does not require the intermediacy of the expensive amino acid D-do-iso