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Stra13 is induced by genotoxic stress and regulates ionizing-radiation-induced apoptosis

✍ Scribed by Thin, Tin Htwe; Li, Li; Chung, Teng-Kai; Sun, Hong; Taneja, Reshma

Book ID
110033258
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
241 KB
Volume
8
Category
Article
ISSN
1469-221X

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## Abstract E2F1, a member of the E2F family of transcription factors, plays a critical role in controlling both cell cycle progression and apoptotic cell death in response to DNA damage and oncogene activation. Following genotoxic stresses, E2F1 protein is stabilized by phosphorylation and acetyla