<p>Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments
Store-Operated Calcium Channels
β Scribed by Murali Prakriya (Eds.)
- Publisher
- Academic Press
- Year
- 2013
- Tongue
- English
- Leaves
- 285
- Series
- Current Topics in Membranes 71
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Table of Contents
Content:
Series Page
Page ii
Copyright
Page iv
Contributors
Pages ix-x
Preface
Pages xi-xii
Murali Prakriya
Previous Volumes in Series
Pages xiii-xvi
Chapter One - Store-Operated Orai Channels: Structure and Function
Pages 1-32
Murali Prakriya
Chapter Two - STIMβORAI Interactions That Control the CRAC Channel
Pages 33-58
Aparna Gudlur, Yubin Zhou, Patrick G. Hogan
Chapter Three - Structure and Function of Endoplasmic Reticulum STIM Calcium Sensors
Pages 59-93
Peter B. Stathopulos, Mitsuhiko Ikura
Chapter Four - On the Stoichiometry of Resting and Activated CRAC Channels
Pages 95-108
Liangyi Chen, Tao Xu
Chapter Five - Alternative Forms of the Store-Operated Calcium Entry Mediators, STIM1 and Orai1
Pages 109-123
James W. Putney
Chapter Six - The ARC ChannelβAn Endogenous Store-Independent Orai Channel
Pages 125-148
Jill L. Thompson, Olivier Mignen, Trevor J. Shuttleworth
Chapter Seven - Contribution and Regulation of TRPC Channels in Store-Operated Ca2Β + Entry
Pages 149-179
Kwong Tai Cheng, Hwei Ling Ong, Xibao Liu, Indu S. Ambudkar
Chapter Eight - Molecular Regulation of the Pore Component of CRAC Channels, Orai1
Pages 181-207
Sonal Srikanth, Yousang Gwack
Chapter Nine - Emerging Roles for Native Orai Ca2+ Channels in Cardiovascular Disease
Pages 209-235
Brian Ruhle, Mohamed Trebak
Chapter Ten - The Neglected CRAC Proteins: Orai2, Orai3, and STIM2
Pages 237-271
Markus Hoth, Barbara A. Niemeyer
Index
Pages 273-281
π SIMILAR VOLUMES
<p>Voltage-gated calcium channels are critical regulators of cytoplasmic levels of calcium, the universal signaling ion. As such, calcium channels trigger a wide range of cellular functions, from muscle contraction to neurotransmitter secretion, and are important players in human disease. Prominent
<p>The drugs named calcium channel blockers (CCBs) were initially termed calΒ cium antagonists (see Chapter 1). They are also designated as calcium entry blockers (CEBs), calcium blockers, calcium channel antagonists, calcium channel inhibitors (and in French anticalciques). As this is reported in s
<p>oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical pharΒ macological t
<p><p>Calcium ions represent Mother Natureβs βion-of-choiceβ for regulating fundamental physiological functions, as they initiate a new life at the time of fertilization and guide subsequent developmental and physiological functions of the human body. Calcium channels, which act as gated pathways fo