A rapid-scanning ultraviolet-visible (UV-vis) detector was interfaced successfully with capillary supercritical fluid chromatography (SFC). The pseudo on-column detection approach was used to produce a detector dead volume of less than 60 nL. High sensitivity (low picogram detection limits), a large
Stopped-flow FTIR detection in capillary supercritical fluid chromatography
β Scribed by Mark W. Raynor; Keith D. Bartle; Anthony A. Clifford; Bernard W. Cook
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 227 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1040-7685
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
A stoppedβflow procedure for capillary supercritical fluid Chromatography with Fourier transform infrared detection is described. The flow of mobile phase is stopped so that the analyte peak is held under liquid conditions in the flow cell while FTIR scans are recorded. An increase in the IR spectrum signalβtoβnoise ratio is demonstrated during the analysis of a polymer additive.
π SIMILAR VOLUMES
## Abstract Methoximation of reducing oligosaccharides, combined with the additional derivatization of hydroxy groups, yields derivatives suitable for capillary supercritical fluid chromatography with thermionic detection. Detection limits on the order of picogramβperβsecond can easily be achieved.
A splitless injection technique, allowing 0.5 pI injectionson 50 pm i.d. columns, has been developed.
## Abstract A new method to accurately deliver small amounts (0.5 to 20 mol%) of modifier into CO~2~ was used to study the effects of three different modifiers (methanol, water, and formic acid) in packed capillary column SFC. The method allows the use of different modifiers, with minimal instrumen
In cases where high efficiency is required to resolve complex mixtures of either thermally labile or nonvolatile organic compounds, capillary supercritical fluid chromatography may be the most desirableanalytical method. Whilegreat strides in this new technology have been made over the last few year