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Stoichiometry of binding of high molecular weight kininogen to factor XIXIa

✍ Scribed by Bonnie J. Warn-Cramer; S.Paul Bajaj


Book ID
115758594
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
332 KB
Volume
133
Category
Article
ISSN
0006-291X

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High-affinity binding of two molecules o
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Human low-molecular-weight kininogen (LK) was shown by fluorescence titration to bind two molecules of cathepsins L and S and papain with high affinity. By contrast, binding of a second molecule of cathepsin H was much weaker. The 2:1 binding stoichiometry was confirmed by titration monitored by los