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Stimulus-secretion coupling of arginine-induced insulin release

✍ Scribed by Abdullah Sener; Leonard C. Best; Allen P. Yates; Marcel M. Kadiata; Elizabeth Olivares; Karim Louchami; Hassan Jijakli; Laurence Ladrière; Willy J. Malaisse

Book ID
111637591
Publisher
Springer
Year
2000
Tongue
English
Weight
195 KB
Volume
13
Category
Article
ISSN
0969-711X

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Stimulus-secretion coupling of arginine-
Stimulus-secretion coupling of arginine-induced insulin release: Significance of changes in extracellular and intracellular pH
✍ Willy J. Malaisse; Pierre O. Plasman; François Blachier; Andre Herchuelz; Abdull 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 559 KB

The possible relevance of changes in extracellular and/or intracellular pH to the insulinotropic action of L-arginine and L-homoarginine was investigated in rat pancreatic islets. A rise in extracellular pH from 7.0 to 7.4 and 7.8 augmented the secretory response to these cationic amino acids whilst