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Stimulus-secretion coupling of arginine-induced insulin release. Functional response of islets to l-arginine and l-ornithine

✍ Scribed by François Blachier; Viviane Leclercq-Meyer; Jocelyne Marchand; Marie-Claire Woussen-Colle; Paulo C.F. Mathias; Abdullah Sener; Willy J. Malaisse


Book ID
118205317
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
596 KB
Volume
1013
Category
Article
ISSN
0167-4889

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Stimulus-secretion coupling of arginine-
✍ Willy J. Malaisse; Pierre O. Plasman; François Blachier; Andre Herchuelz; Abdull 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 559 KB

The possible relevance of changes in extracellular and/or intracellular pH to the insulinotropic action of L-arginine and L-homoarginine was investigated in rat pancreatic islets. A rise in extracellular pH from 7.0 to 7.4 and 7.8 augmented the secretory response to these cationic amino acids whilst