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Stimulus-secretion coupling of amino acid-induced insulin release VII. The B-cell memory for L-glutamine

✍ Scribed by G. Somers; A.R. Carpinelli; G. Devis; A. Sener; W.J. Malaisse

Book ID
118948450
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
910 KB
Volume
31
Category
Article
ISSN
1532-8600

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The stimulus-secretion coupling of amino
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Aminooxyacetate, an inhibitor of cytosolic transamination reactions, inhibited insulin release evoked by either 2-ketoisocaproate or L-leucine in rat pancreatic islets incubated in the presence of L-glutamine or L-asparagine. As a rule, aminooxyacetate also inhibited the oxidation of these nutrient