In mixed glial cell cultures from cerebral cortices of newborn rats, endotoxin induces nitric oxide (NO) production in microglial cells. Earlier we demonstrated that endotoxin induced NO production by microglial cells is inhibited in the presence of astroglial cells by transforming growth factor β€ (
Stimulation of tissue plasminogen activator production from epithelial cell lines
β Scribed by Asgar Electricwala; Bryan Griffiths
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 464 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0263-6484
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Urokinase plasminogen activator (u-PA) and its fast acting type-1 inhibitor (PAI-1) localize to cellular focal adhesive structures and the ajoining proximal undersurface region, respectively (Kutz et al., J. Cell. Physiol. 176:8-18, 1997). PAI-1 may function in this locale to modulate pericellular p
Supernatants of a mclnnorna cell line were chromatographed on five affinity supports to ev;ilu;itr and compare purification protocols for isolation of tissue-type plasminogen activator (t-Pa). t-PA was adsorbed qunntitittively from cell culture supernatants by lysine-Sepharose, concanavulin -A-Sepha
Transit of serumstimulated normal rat kidney (NRK) epthelial cells through the first division cycle after release from quiescence (G 0 ) provided a model system to assess the kinetics and mechanisms underlying PAI-1 expression in a growth "activated" phenotype. PAI-1 mRNA transcripts increased by mo
Our recent morphologic studies indicated that peripheral nervous system (PNS) adrenergic neurons synthesize, transport, and store the serene protease, tissue plasminogen activator (t-PA) in axon terminals, many of which innervate vessel walls. Sympathoadrenal stimulation induces a surge of t-PA from