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Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

โœ Scribed by de Jonge, Wouter J; van der Zanden, Esmerij P; The, Frans O; Bijlsma, Maarten F; van Westerloo, David J; Bennink, Roelof J; Berthoud, Hans-Rudolf; Uematsu, Satoshi; Akira, Shizuo; van den Wijngaard, Rene M

Book ID
109923144
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
436 KB
Volume
6
Category
Article
ISSN
1529-2908

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## Abstract ## Objective S100A4 has been shown to be increased in osteoarthritic (OA) cartilage and to stimulate chondrocytes to produce matrix metalloproteinase 13 (MMPโ€13) through activation of the receptor for advanced glycation end products (RAGE). The aim of this study was to examine the mech