## Abstract ## Objective S100A4 has been shown to be increased in osteoarthritic (OA) cartilage and to stimulate chondrocytes to produce matrix metalloproteinase 13 (MMPโ13) through activation of the receptor for advanced glycation end products (RAGE). The aim of this study was to examine the mech
โฆ LIBER โฆ
41 INTERLUKIN-7 STIMULATES SECRETION OF S100A4 BY ACTIVATING THE JAK-STAT PATHWAY IN HUMAN ARTICULAR CHONDROCYTES
โ Scribed by R.R. Yammani; D. Long; R. Loeser
- Book ID
- 114350193
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 42 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1063-4584
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## Abstract ## Objective S100 proteins have been implicated in various inflammatory conditions, including arthritis. The aims of this study were to determine whether chondrocytes produce S100A4 and whether S100A4 can stimulate the production of matrix metalloproteinase 13 (MMPโ13) by articular cho