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Stimulation of prostaglandin E2 and bone resorption by recombinant human interleukin 1 alpha in fetal mouse bones

✍ Scribed by Kanji Sato; Yuko Fujii; Keizo Kasono; Motoyasu Saji; Toshio Tsushima; Kazuo Shizume

Book ID
117057323
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
339 KB
Volume
138
Category
Article
ISSN
0006-291X

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The cytokine interleukin-6 (IL-6) was produced by neonatal mouse parietal bones during a 6- or 48-hour culture period in response to prostaglandin E2 (PGE2) and bovine parathyroid hormone (PTH) 1-34 fragment but not 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]. At the same time there was an increase in ta