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In vivo inhibition of localized bone resorption by human recombinant interleukin-1 receptor antagonist

✍ Scribed by Richard A. Chole; Brian T. Faddis; Steven P. Tinling


Book ID
112119406
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
369 KB
Volume
10
Category
Article
ISSN
0884-0431

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Human recombinant interleukin-1 receptor
✍ R. A. Chole; S. P. Tinling; B. T. Faddis πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 397 KB

Both interleukin-1 alpha (IL-1 alpha) and interleukin-1 beta (IL-1 beta) are powerful stimulators of bone resorption in vivo and in vitro. Interleukin-1 receptor antagonist (IL-1ra) binds to many interleukin-1 receptors. It does not activate the receptor and effectively blocks the action of IL-1 alp