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Stimulation of polyphosphoinositide hydrolysis in Swiss 3T3 cells by recombinant fibroblast growth factors

โœ Scribed by Kenneth D. Brown; Diana M. Blakeley; David R. Brigstock

Book ID
115922409
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
431 KB
Volume
247
Category
Article
ISSN
0014-5793

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Epidermal Growth Factor (EGF) at concentrations of 10(-9) to 10(-10) M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.