Monocyte/macrophage polypeptides (monokines) alter the properties of synovial cells. This interaction could explain some of the properties of the inflamed synovium in rheumatic disease. Only recently has it been possible to test the action of purified monokines on the target synovial cells. We repor
Stimulation of interleukin-1α and interleukin-1β release from human monocytes by cyanogen bromide peptides of type ii collagen
✍ Scribed by Makoto Goto; Sadayoshi Yoshinoya; Terumasa Miyamoto; Minoru Sasano; Masahiro Okamotoy; Kusuki Nishioka; Kuniaki Terato; Yutaka Nagai
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 633 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Hyaluronan accumulation in the retroorbital connective tissue is one of the pathological features of Graves' ophthalmopathy. Interleukin‐1β (IL‐1β) is known to stimulate hyaluronan synthesis in orbital fibroblasts. In the present study, the intracellular signal transduction pathways inv
The effects were examined of baicalein on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) production stimulated by interleukin-1␣ (IL-1) and tumour necrosis factor-␣ (TNF-␣) in cultured human vein umbilical endothelial cells (HUVECs). IL-1 and TNF-␣ increased