Stimulation of indirubin production by KNO3depletion in indole-supplemented suspension culture ofPolygonum tinctorium

✍ Scribed by I. S. Chung; T. Kim; G. W. Bae; H. J. Lee; Y. A. Chae

• Book ID: 104645900
• Publisher: Springer Netherlands
• Year: 1996
• Tongue: English
• Weight: 241 KB
• Volume: 18
• Category: Article
• ISSN: 0141-5492
• DOI: 10.1007/bf00154627

✦ Synopsis

Indole when added at 20 mM to shake flask cultures of Polygonum tinctorium cells on 16th day increased indirubin production from 41 mg/l to 126 mg/l. Use of KNO3 depleted media stimulated indirubin formation up to 88% and 26% in shake flasks and air-lift bioreactors, respectively.